Health officials in the US believe a nurse infected with Ebola may have been sick and contagious for four days - and took two flights - before diagnosis.
They believe Amber Vinson may have become ill as early as last Friday, when she flew from Dallas to Ohio.
Disease control specialists are being sent to Ohio to help monitor people she came into contact with there.
The virus has killed more than 4,000 people, almost all in West Africa, but infections are increasing in the West.
Former UN Secretary General Kofi Annan has said he is "bitterly disappointed" with the international response.
In an interview with the BBC's Newsnight programme, Mr Annan said richer countries should have moved faster.
For the second day running, US President Barack Obama met with top officials involved in the Ebola containment in the US.
He repeated his resistance to growing demands from Republicans to implement a travel ban to the US from countries ravaged by the illness, saying it would not be effective.
And referring to Ms Vinson, he said: "It is very important that we are monitoring and tracking anyone who was in close proximity to this second nurse."
She is the second nurse to have become infected while caring for a Liberian Ebola patient in Dallas.
The Centers for Disease Control and Prevention (CDC) now believes Ms Vinson may have had a slight fever when she travelled home to Cleveland, Ohio, last Friday.
The agency wants to interview passengers on her Dallas to Cleveland flight as well as her return flight five days later.
She was diagnosed with Ebola on Tuesday, the morning after flying home to Texas.
Lets Pray for America and Americans
culled from BBC
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